Rabeprazole sodium delayed-release multiparticulates: Effect of enteric coating layers on product performance
نویسندگان
چکیده
منابع مشابه
Formulation and evaluation of rabeprazole sodium delayed release tablets
The main purpose of this work is to develop delayed release stable tablet formulation of Rabeprozole sodium by direct compression and wet granulation method and enteric coating of tablets. All enteric coated tablets are delayed release tablets but all delayed release tablets are not enteric coated tablets. The present work aims to avoid degradation of drug in acidic environment of stomach. Pref...
متن کاملSustained Release Multiparticulates via Powder Coating
Hydrophobic grade fumed silicas are generally used in tabletting as lubricants. They are also found to retard the release of pharmaceutical actives. This is because of their hydrophobic nature, which gives good cohesive and adhesive properties. considering this point it was thought that they could be used as dry coating agents for solid dosages forms. The model drug selected for this work was p...
متن کاملSustained Release Multiparticulates via Powder Coating
Hydrophobic grade fumed silicas are generally used in tabletting as lubricants. They are also found to retard the release of pharmaceutical actives. This is because of their hydrophobic nature, which gives good cohesive and adhesive properties. considering this point it was thought that they could be used as dry coating agents for solid dosages forms. The model drug selected for this work was p...
متن کاملsustained release multiparticulates via powder coating
hydrophobic grade fumed silicas are generally used in tabletting as lubricants. they are also found to retard the release of pharmaceutical actives. this is because of their hydrophobic nature, which gives good cohesive and adhesive properties. considering this point it was thought that they could be used as dry coating agents for solid dosages forms. the model drug selected for this work was p...
متن کاملDevelopment and validation of dissolution testings in acidic media for rabeprazole sodium delayed-release capsules
Rabeprazole sodium (RAB) dissolved in acidic media is accompanied by its degradation in the course of dissolution testing. To develop and establish the accumulative release profiles of ACIPHEX(®) Sprinkle (RAB) delayed-release capsules (ACIPHEX(®) Sprinkle) in acidic media using USP apparatus 2 (paddle apparatus) as a dissolution tester, the issues of determination of accumulative release amoun...
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ژورنال
عنوان ژورنال: Journal of Advanced Pharmaceutical Technology & Research
سال: 2011
ISSN: 2231-4040
DOI: 10.4103/2231-4040.85539